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Doktorandenstipendium
Am Interdisziplinären Zentrum für Neurowissenschaften (IZN) – Abteilung Neurobiologie der Universität Heidelberg ist ein
DOKTORANDENSTIPENDIUM
zu vergeben
Thema: Investigating the NMDAR and TPRM4 interaction in the context of chronic pain, with particular emphasis on neuropathic pain models.
Laufzeit: 9 Monate
Beginn: 1. März 2025
Höhe des Stipendiums: EUR 13.212,-
Herkunft der Mittel: Universität Heidelberg / Neurobiologie
Bewerbungsschluss: 31.01.2025
Bewerbungen in englischer Sprache (Lebenslauf, Motivationsschreiben) richten Sie bitte an sekretariat@nbio.uni-heidelberg.de
Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain
This study describes a previously unappreciated mechanism of astrocyte-neuron metabolic communication through glycogen breakdown in the spinal cord that fuels spinal neuron hyperexcitability.
Cellular and Molecular Mechanisms Underlying Pain Chronicity
Chronic pain affects a significant amount of the population and is responsible for vast worldwide socio-economic costs. Moreover, conventional therapies are not very effective in reducing pain; in fact, clinicians report only 50 percent pain relief among patients who respond to treatments. Since chronic pain is not a pure prolongation of acute pain, but is based on structural and functional alterations of neural circuity, understanding the molecular mechanisms underlying these alterations is crucial for developing new effective therapies.
